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Dr. Rodrigo Díaz

Cargo: 
Dpto. de Biología.
E-mail: 
rodrigo.diaz.e@usach.cl
Biografía: 

PhD in Molecular Biophysics, University of Texas, 2011, USA. Ingeniero en Biotecnología Molecular, Universidad de Chile, 2006,

Lineas de Investigación: 

Bioquímica Evolutiva y Bionanotecnología

Proyectos: 
  • Ensamblaje y Actividad de Amiloides Catalíticos Prebióticos. DICYT Postdoctorado, USACH (2023-2025). Patrocinante
  • Exploring The Use Of Amyloids As Minimalist Enzymes For Industrial Applications. FONDECYT EXPLORACION. (2022-2025) Director
  • An Experimental Study of the Involvement of Catalytic Amyloids on Prebiotic Chemistry FONDECYT Regular, ANID. (2021-2025) Investigador Responsable.
  • Caracterización de la reactividad catalítica del péptido beta amiloide y su relación con la formación de amiloides. DICYT Postdoctorado, USACH (2019-2020) Profesor Patrocinante.
Últimas Publicaciones: 

9.- Duran-Meza E, Araya-Secchi R, Romero-Hasler P, Soto-Bustamante EA, Castro-Fernandez V, Castillo-Caceres C, Monasterio O, Diaz-Espinoza R. (2024). Metal Ions Can Modulate the Self-Assembly and Activity of Catalytic Peptide Amyloids. Langmuir

8.- Arcos J, Grunenwald F, Sepulveda D, Jerez C, Urbina V, Huerta T, Troncoso-Escudero P, Tirado D, Perez A, Diaz-Espinoza R, Nova E, Kubitscheck U, Rodriguez-Gatica JE, Hetz C, Toledo J, Ahumada P, Rojas-Rivera D, Martín-Montañez E, Garcia-Fernandez M, Vidal RL. (2023). IGF2 prevents dopaminergic neuronal loss and decreases intracellular alpha-synuclein accumulation in Parkinson's disease models. Cell Death Discovery

7.- Ventura S, Kogan MJ, Diaz-Espinoza R. (2023). Peptide assemblies in nanotechnology Frontiers in Molecular Biosciences.

6.- Diaz-Espinoza R. (2022). Catalytically Active Amyloids as Future Bionanomaterials. Nanomaterials

5.- Diaz-Espinoza R. (2021). High-Resolution Structures of Amyloids Involved in Neurodegenerative Diseases. Frontiers in Aging Neuroscience

4.- Duran-Meza E, Diaz-Espinoza R. (2021).  Catalytic Amyloids as Novel Synthetic Hydrolases. International Journal of Molecular Sciences

3.- Castillo-Caceres C, Duran-Meza E, Nova E, Araya-Secchi R, Monasterio O, Diaz-Espinoza R. (2020). Functional characterization of the ATPase-like activity displayed by a catalytic amyloid. Biochimica et Biophysica Acta - General Subjects

2.- Diaz-Espinoza R, Nova E, Monasterio O. (2020). Corrigendum to "Overcoming electrostatic repulsions during amyloid assembly: Effect of pH and interaction with divalent metals using model peptides" [Arch. Biochem. Biophys. 621 (2017) 46-53]. Archives of Biochemistry and Biophysics

1.- Diaz-Espinoza R, Morales R, Concha-Marambio L, Moreno-Gonzalez I, Moda F, Soto C. (2018). Treatment with a non-toxic, self-replicating anti-prion delays or prevents prion disease in vivo. Nature Molecular Psychiatry.