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Dra. Yesseny Vásquez
Doctorate in Chemistry from the University of Santiago de Chile
Biomedicine
- “Synthesis, in sillico and in vitro evaluation of biaryl ethanones, propanones and propenones as antivirulence agents against Methicillin Resistant Staphylococcus aureus (MRSA)” Fondecyt regular 1240399. (2024-2028). Principal Researcher
- Strengthening genomic surveillance of Acinetobacter baumannii in Latin America through the establishment of a Chile-Mexico collaboration axis” Chile-Mexico Cooperation Fund No. 190 (2024-2025) Director
- Establishment of a Chile-Mexico collaboration axis for genomic surveillance of the SARS-CoV-2 virus in Latin America: technical and academic exchange to strengthen epidemiological surveillance capacities in the region Chile-Mexico Cooperation Fund No. 182 (2023-2024) Alternate Director
- Genomic characterization of aquatic birnaviruses detected in Antarctic fish of the genus Notothenia: Searching for the key to the adaptation of fish viruses to near-freezing temperatures. INACH (2020-2022). Alternate Director
- Synthesis of Organics and Organometallics analogs of isoflavonoids: A new pharmacophore for in-vitro and in-silico studies as dual 5-LOX and COX-2 inhibitors FONDECYT (2020-2023). Co-Researcher
- “Strengthening interdisciplinary study through proteomic analysis and quantification of metabolites produced by microorganisms of importance in the food industry through the acquisition of a uHPLC-Ms/Ms system” EQM180076 FONDEQUIP (2018-2020). Co-Researcher
- “Prenylated polyphenols with antibacterial activity and their ability to combat Staphyloccocus aureus resistance to commercial antibiotics by generating reactive oxygen species (ROS).” DICYT-USACH (2019-2022). Principal Researcher
- Methylcillin-resistant Staphylococcus aureus isolated from patients of two Hospitals of the Metropolitan Health Service healthcare network: Characterization of its virulence factors using molecular biology tools.” DICYT Clinico_USACH (2019-2021) Principal Researcher
17.- Nuñez D, Jiménez P, Cortez-San Martín M, Cortés C, Cárdenas M, Michelson S, Garay T, Vecchiola M, Céspedes A, Maldonado J, Vásquez-Martínez Y (2024). Molecular and phylogenomic analysis of a vancomycin intermediate resistance USA300LV strain in Chile Microorganisms.
16.- Cárdenas M, Michelson S, Galleguillos C, Vásquez-Martínez Y, Cortez-San Martín M. (2024). Modulation of infectious Salmon Anaemia virus infection by clathrin-mediated endocytosis and macropinocytosis inhibitors Research in veterinary Science.
15.- Osorio-Olivares M, Vásquez-Martínez Y, Díaz K, Canelo J, Taborga L, Espinoza-Catalán L (2024) Antibacterial and antioxidant activity of synthetic polyoxygenated flavonoids. International Journal of Molecular Sciences.
14.- Cerda A, Rivera M, Armijo G, Ibarra-Hernández C, Reyes J, Blázquez-Sánchez P, Avilés J, Seguel A, Brown A, Vásquez Y, Cortez-San Martín M, Cubillos F, Gutierrez R (2024). An Open One Step RT-qPCR for SARS-CoV-2 detection PloS One.
13.- Navarrete E, Morales P, Muñoz-Osses M, Vásquez-Martínez Y, Godoy F, Maldonado T, Martí A, Flores E, Mascayano C (2023). Evaluating the inhibitory activity of ferrocenyl Schiff bases derivatives on 5-lipoxygenase: Computational and biological studies Journal of Inorganic Biochemistry.
12.- Cárdenas M, Michelson S, Pérez D., Montoya M., Toledo J., Vásquez-Martínez Y, Cortez- San Martin M (2022). Infectious Salmon Anemia Virus Infectivity Is Determined by Multiple Segments with an Important Contribution from Segment 5 Viruses
11.- Osorio M, Carvajal M, Vergara A, Butassi E, Zacchino S, Mascayano C, Montoya M, Mejias S, Cortez-San Martín M, Vásquez-Martínez Y. (2021). Prenylated Flavonoids with Potential Antimicrobial Activity: Synthesis, Biological Activity, and In Silico Study International Journal of Molecular Sciences
10.- Lozano_Muñoz I, Wacyk J, Kretschmer C, Vásquez-Martínez Y, Cortez-San Martín M. (2021). “Antimicrobial resistance in Chilean marine-farmed salmon: Improving food safety through One Health” One Health
9.- Muñoz-Osses M, Quiroz J, Vásquez-Martínez Y, Flores E, Navarrete E, Godoy F, Torrent C, Cortez-San Martín M, Gómez A, Mascayano C. (2021). Evaluation of cyrhetrenyl and ferrocenyl precursors as 5-lipoxygenase inhibitors, biological and computational studies New Journal of Chemistry.
8.- Valdés E, González C, Díaz K, Vásquez-Martínez Y, Mascayano C, Torrent C, Cabezas F, Mejas S, Montoya M, Cortez-San Martín M, Muñoz M, Joseph-Nathan P, Osorio M, Taborga L. (2020). “Biological Properties and Absolute Configuration of Flavanones from Calceolaria thyrsiflora Graham” Frontiers in Pharmacology
7.- Flores E., Muñoz-Osses M, Torrent C, Vásquez-Martínez Y, Gómez A, Cortez-San Martín M, Vega A, Martí A, Godoy F, Mascayano C (2020). Design, Synthesis and Biological Evaluation of Ferrocenyl Thiazole and Thiazolo[5,4‐d]thiazole Catechols as Inhibitors of 5‐hLOX and as Antibacterials against Staphylococcus aureus Organometallics
6.- Cárdenas M, Galleguillos C, Avevedo K, Ananias C, Alarcón J, Michelson S, Toledo J, Montoya M, Meneses C, Castro-Nallar E, Vásquez-Martínez Y, Cortez-San Martín M (2020). “Rapid sequence modification in the highly polymorphic region (HPR) of the hemagglutinin gene of the infectious salmon anaemia virus (ISAV) suggests intra-segmental template switching recombination” Journal of Fish Diseases
5.- Carol López de Dicastillo, Cristian Patiño, María José Galotto, Yesseny Vásquez-Martínez, Claudia Torrent, Alejandro Pereira, and Juan Escrig (2019). "Novel hollow titanium dioxide nanospheres with interface antimicrobial activity against resistant bacteria to reduce microbial incidence" Beilstein Journal of Nanotechnology
4.- Yesseny Vásquez-Martínez, Claudia Torrent, Giannina Toledo, Francisco Cabezas, Victoria Espinosa, Margarita Montoya_K, Sophia Mejias, Marcelo Cortez-San Martín, Silvia Sepúlveda-Boza, Carolina Mascayano (2019). “New Antibacterial and 5-lipoxygenase activities of synthetic benzyl phenyl ketones:biological and docking studies Bioorganic Chemistry.
3.- Yesseny A. Vásquez-Martínez; Mauricio E. Osorio; Diego A. San Martín; Marcela A. Carvajal; Alejandra P. Vergara; Elizabeth Sanchez; Marcela Raimondi; Susana A. Zacchino; Carolina Mascayano; Claudia Torrent; Francisco Cabezas; Sophia Mejias; Margarita Montoya; Marcelo Cortez‑San Martín. (2019). "Antimicrobial, Anti-Inflammatory and Antioxidant Activities of Polyoxygenated Chalcones" Journal Brazilian Chemical Society
2.- Yesseny A. Vásquez-Martínez; Mauricio E. Osorio; Diego A. San Martín; Marcela A. Carvajal; Alejandra P. Vergara; Elizabeth Sanchez; Marcela Raimondi; Susana A. Zacchino; Carolina Mascayano; Claudia Torrent; Francisco Cabezas; Sophia Mejias; Margarita Montoya; Marcelo Cortez‑San Martín. (2019). "Antimicrobial, Anti-Inflammatory and Antioxidant Activities of Polyoxygenated Chalcones" Journal Brazilian Chemical Society
1.- Toro-Ascuy D, Santibañez A, Peña V, Beltran-Pavez C, Cottet L, Molina C, Montoya M, Sandoval N, Vásquez-Martínez Y, Mascayano C, Cortez-San Martín M. (2019). Development of an Isavirus minigenome system to study to function of the pocker RNA-binding domain of the viral nucleoprotein (NP) in salmon cells. Journal of Fish Diseases